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Brooks Glycerin 22 (2025 review): An Incredible New Cushioning?

Brooks Glycerin 22 review

Brooks is one of the most popular brands in the world (number 1 in the United States). Its range is quite classic, notably featuring the DNA LOFT foam on almost all of its models.

It was time to innovate, and Brooks does so with this Glycerin 22 introducing a new foam.

Does it change the DNA of the series? Is it better to opt for this model or the Max version? Does it suit your runner profile and your goals?

This is what we will study in this complete review.

Why trust me?

With a marathon personal best of 2:38 and a significant weekly training volume, I have the opportunity to test many running shoe models to help my practice.

I’ve conducted my field test of the Brooks Glycerin 22 during various types of sessions to evaluate their comfort and running sensations. Additionally, I’ve consulted other runners of different levels to validate my sensations and ensure my recommendations will be helpful to as many runners as possible.

test Brooks Glycerin 22

Our verdict

9.3Overall Score

Very good shoes, very comfortable and more versatile due to their new foam.

  • Weight: 262 g (size 42)
  • Foam: DNA TUNED
  • Height: 38 mm (heel), 28 mm (forefoot)
  • Drop: 10 mm
  • Training, all distances

The Brooks Glycerin 22 benefits from a new foam that alone warrants upgrading.

DNA TUNED thus replaces DNA LOFT V3 with a very well-balanced feel (leaning towards plushness) and a very good shock absorption. Moreover, different densities also allow a satisfying responsiveness.

The new technical double jacquard knit upper offers the characteristic comfort of the brand while the RoadTack rubber ensures a good grip on wet surfaces.

In summary, this new Glycerin 22 remains true to the series while offering something different and successful. A premium shoe for daily training.

Pros

  • Very good shock absorption for long distances
  • More comfortable and well-fitted upper
  • Stable and plush cushioning
  • Effective traction on all surfaces
  • Better responsiveness than the previous version

Cons

  • Upper could be more breathable
  • Varying experience depending on foot strike

Cushioning

Brooks Glycerin 22 midsole cushioning

Preferences in terms of cushioning vary widely among runners. That’s why a test shouldn’t rely on just one person’s opinion.

I’ve tested most of the latest models from the American brand and stayed objective despite fairly firm sensations which I don’t particularly like.

The DNA LOFT V3 foam of the previous version (and other key Brooks models like the Ghost 16 and the Adrenaline 24) has many qualities but a rather rigid feel.

DNA LOFT V3 foam Brooks Glycerin 22

So I was quite curious to test this new Brooks Glycerin 22 with the DNA TUNED foam in the midsole, introduced as revolutionary by the brand.

The nitro-injection process is not recent and has been used by Brooks for a long time. The novelty here comes from different densities at the heel and forefoot.

The compound was created to “foam” differently but in a single block:

  • Smaller cells found at the front prioritize reactivity and energy return
  • Larger cells at the heel prioritize cushioning
julien guyod testing Brooks Glycerin 22

The feel is very well-balanced, closer to plush (especially if heel striking) for an enjoyable running experience. The dimensions do not change: 38 mm under the heel and 28 mm under the metatarsal.

Shock absorption is very good and makes long distances feasible. According to the brand, the new foam offers “infinite” energy as the run goes on.

Even though we’re far from the energy savings offered by a carbon plate, I did find no loss as the run progressed.

On some shoes, a thickness of 27-28 mm at the front could hinder passing the 30 km mark, but this wasn’t the case with these running shoes.

Finally, the 10 mm drop is classic and should suit a wide variety of runners.

Energy Return

Glycerin 22 Brooks test

With a weight of 262 g in 42, the shoe is lighter than many competitors, but cannot be described as light.

Responsiveness is clearly better than the previous version, but the experience varies depending on foot strike.

Pure heel strikers will not benefit from the smaller, more reactive cells present at the front and will find the shoe moderately dynamic.

I was pleasantly surprised to find that the shoe is capable of accelerating when needed. The rocker is rather low but ensures a smooth transition between heel and toe.

Support and Stability

Brooks Glycerin 22 heel

The shoe is for neutral gait and doesn’t feature technology to stabilize. Note there is a GTS (Go To Support) version for pronators.

Nonetheless, the wide base and reliable outsole provide effective stability (standard) and a safe ride.

Foot Lockdown

The new technical double jacquard knit upper is similar to what Brooks usually offers, meaning a success.

Brooks Glycerin 22 technical mesh upper

The brand’s expertise results in quite thin uppers but with very good comfort.

The numerous paddings (it’s surprising the shoe isn’t heavier) offer excellent comfort, and they can be worn for a long time.

As is often the case with double layer knit uppers, some testers note that breathability could be better. During the winter season, I personally did not notice this.

In terms of fit, the shoe is stretchy and hugs the foot very well without compressing it. The structure is also very good due to lateral and midfoot reinforcements.

Brooks Glycerin 22 technical upper

The Brooks Glycerin 22 fits true to size – no tester reported sizing issues.

There are also wide and narrow versions if needed. Not all stores necessarily stock them, but you will find them on Brooks’ official website.

The heel counter is effective, with a loop to facilitate slipping on.

The only potential downside: the tongue is not gusseted. It is very (too?) thick and some runners note slipping.

Finally, the classic laces complete a good foot lock.

Traction

Brooks Glycerin 22 rubber outsole

The shoe’s outsole uses RoadTack technology. It is a mix of recycled rubber and silica covering a large part of the surface, especially the impact zones. The foam is exposed in some areas.

The result gives good traction: the shoe adheres well to wet surfaces.

The numerous grooves ensure good flexibility and make the Glycerin 22 a fairly flexible shoe.

In addition to asphalt, you will be able to use these shoes on most non-technical paths or trails.

Use Scenarios

Brooks Glycerin 22 rubber outsole

The Brooks Glycerin 22 will accompany you in your training over all distances thanks to its very effective cushioning that optimally absorbs impacts.

From recovery jogs to the traditional long run, expect no restrictions.

According to us, this model is well-suited for all profiles, including beginners and heavier runners.

As I mentioned earlier, the shoe reportedly delivers more energy as the run progresses according to the brand. This is an argument difficult to verify and seems more like a marketing claim.

In any case, it’s true that I didn’t feel fatigue set in over long distances as could happen with heavy shoes.

Brooks Glycerin 22 tongue and laces

This may stem from my forefoot strike. Indeed, the cells are more reactive at the front, which can help maintain rhythm more easily. However, other heel-striking runners described the same experience, so the foam’s efficiency may apply to everyone.

Regarding responsiveness, heel-strikers will not notice significant differences with the V21 and will use the shoe more for moderate-paced runs.

For my part, I found the dynamism surprising. Not speaking of speed, I was able to maintain tempo paces without too much difficulty. That said, it would not be my primary choice for races and fast sessions — there are more performant alternatives for that.

Quality and Durability

Brooks Glycerin 22 running shoes

No (bad) surprise on that front.

The brand’s typical longevity is found here with a robust outsole and good quality mesh.

Durability is therefore quite standard, making the Brooks Glycerin 22 offer good value for money.

The upper uses 61% recycled materials, and these shoes are vegan.

Alternatives

Brooks Glycerin 22 vs 21

The following updates are noted for this new version:

  • New DNA TUNED cushioning technology (like the Brooks Glycerin Max)
  • New well-fitted upper for more comfort

The update might seem minor. This is true in the sense that both versions are excellent training partners. However, I find that the new foam alone justifies opting for the v22.

Brooks Glycerin Max 2

Despite its name, the Max ultimately only offers a mere millimeter more height under the heel compared to the Glycerin 22.

However, the low drop (6 vs 10 mm) results in a more cushioned forefoot: 33 mm versus 29 mm.

The Glycerin 22 is lighter and benefits from a more reactive cutting-edge foam.

The choice will primarily depend on your preferences in terms of drop and forefoot cushioning.

Conclusion

pair of Brooks Glycerin 22 running shoes

The Brooks Glycerin 22 is a beautiful update of an already very popular series. The brand offers a new innovative (and successful) foam that provides a good running experience and versatility.

These shoes won’t be for you if you are looking for pure performance, but they are a very good option if your priorities are comfort and protection (even for a marathon).

Facts

Reference: official site

Julien Guyod

Julien Guyod

Julien Guyod, 40, is a math teacher and freelance writer. He took up running in 2015 and specializes in marathons, clocking in with a 2:38 personal best at the La Rochelle marathon in France. He's passionate about running shoes and loves to share his impressions of the models he's tested, always pushing the mileage further to discover more insights!

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